Opportunities in Austin, TX, United States

Senior Engineering Manager — Lab Execution Platform : Women’s Health

About the Role

This is your chance to own a platform that lab scientists rely on every single day—and to rebuild it from the ground up. You'll lead maintenance of our off-the-shelf Lab Execution System while driving its transition to a custom, in-house platform. Every improvement you ship makes lab operations faster, makes scientists' lives easier, and ultimately helps improve patient health outcomes. The work is real, the impact is immediate, and the customers are just down the hall.

You'll treat Lab Operations and R&D as your primary customers, partnering with them to build an intuitive, efficient, scalable Lab Execution platform they'll love using. You'll lead a small, sharp team in a fast-moving Kanban or Scrum workflow, lean hard into a "do more with less" mindset, and put AI to work multiplying what your engineers can accomplish. You'll stay close to the code while leading with impact and kindness, because the best teams are healthy teams.

Key Responsibilities

Technical Leadership & Development

• Own the design, build, and maintenance of both the off-the-shelf and custom Lab Execution platforms, keeping high-throughput lab processes running without a hitch.

• Build an AI-forward team that reaches for modern tooling to move faster and ship smarter.

• Stay hands-on—dive into the code and test the system yourself to make it better.

• Build and scale cloud-based microservices and front-end applications that power real lab workflows.

• Set the bar for technical excellence: reliability, performance, and a user experience people actually enjoy.

• Own the CI/CD pipeline and lock in quality with automated testing.

• Architect infrastructure that scales effortlessly and stays cost-smart.

Customer-Focused Collaboration

• Be the bridge between engineering and lab users, turning real-time feedback into rapid improvements.

• Build tight relationships with Lab Operations, R&D, and stakeholders so their needs steer the roadmap.

• Run a nimble Kanban (or Scrum) workflow that flexes with the lab's evolving needs.

Team Leadership & Management

• Coach and grow a small, agile team, fueling their technical and professional development.

• Juggle priorities, deadlines, and resources—without dropping the bar on quality.

• Spark an ownership mindset so every engineer feels the impact of what they ship.

Process Optimization & Agile Execution

• Relentlessly streamline how the team works—maximum output, minimum overhead.

• Champion modular, cloud-native design as the default way you build.

• Watch performance closely, squash issues before they spread, and keep the platform rock-solid.

Qualifications

Required Skills & Experience

• 10+ years building software applications.

• A track record of leading and growing high-performing engineering teams.

• Expertise in Python, TypeScript, and React, with strong front-end development chops.

• Proficiency with AWS services (Lambda, RDS, DynamoDB, S3, Glue) and infrastructure as code.

• Strong relational database skills (MySQL/PostgreSQL) and SQL programming.

• Experience with messaging frameworks such as Kafka.

• Sharp problem-solving instincts and a quality-first mindset.

• Excellent communication and stakeholder-management skills—you can speak engineer and non-engineer fluently.

Nice to Have

• Experience building custom LIMS/LES systems.

• Hands-on experience with LabVantage.

• Based in Austin, TX, to work shoulder-to-shoulder with lab operations and gather live feedback.

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Austin, TX

$186,200—$232,800 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:

• BBB announcement on job scams
• FBI Cyber Crime resource page