Head of DeFi

This position is listed on behalf of a partner company, who manages all applications and next steps. Our partner is looking for a Head of DeFi based in United States. This is a senior commercial leadership role working closely with executive and product leadership to drive growth across a DeFi-focused product portfolio. You’ll lead partnerships, DeFi integrations, strategic alliances, and business development initiatives across the broader on-chain financial ecosystem. The role combines commercial strategy with hands-on relationship building, market intelligence, deal execution, and product feedback. You’ll engage directly with crypto-native funds, DeFi curators, protocol founders, and other ecosystem participants to identify and develop high-value opportunities. Your understanding of liquidity, TVL, lending, borrowing, DEXs, stablecoins, governance, and on-chain capital flows will inform both partnerships and product strategy. This is an entrepreneurial, high-ownership environment suited to someone who can operate independently, build relationships quickly, and turn strategic opportunities into measurable growth.

Support senior leadership with business development across product verticals, including partner pipeline management, CRM updates, call notes, commercial materials, research, and project coordination. Develop and contribute a strategic perspective to the organization’s overall commercial and growth strategy. Identify market opportunities, partnership opportunities, and strategic alliances that can strengthen competitive positioning and accelerate market share. Build and maintain intelligence on target accounts, market developments, competitors, protocols, funds, and broader DeFi trends. Leverage an established professional network to create introductions, open strategic conversations, and accelerate commercial opportunities. Collaborate closely with leadership and product teams to develop and execute growth strategies across the product portfolio. Lead or support negotiations with strategic partners, helping move opportunities from initial engagement through agreement and integration. Build relationships with the broader DeFi community and existing customers to understand market needs, challenges, and emerging opportunities. Gather customer and ecosystem feedback and translate relevant insights into product roadmaps and development initiatives. Support DeFi integrations and strategic alliances that expand adoption, liquidity, and ecosystem participation. Monitor developments across lending, borrowing, CDPs, DEXs, yield-bearing stablecoins, and other on-chain financial applications to identify opportunities for growth. Contribute to an entrepreneurial, high-performance commercial culture through independent ownership, initiative, and execution. Requirements Demonstrated commercial success, with a track record of closing significant deals and strategic alliances and the ability to clearly explain how opportunities were developed and successfully executed. Strong negotiation and closing skills, with the confidence to advocate for commercial terms, influence stakeholders, and drive deals forward. Deep, pre-existing relationships across liquid crypto-native funds, DeFi curators, and established protocol founders. Strong DeFi expertise and a demonstrated history of driving measurable growth in areas such as total value locked (TVL), liquidity, or protocol adoption. Deep understanding of value flows and business models across lending, CDPs, DEXs, and yield-bearing stablecoins, including the factors required for different categories to succeed. Practical knowledge of DeFi infrastructure and capital allocation, including experience working as or alongside curators, allocating capital into on-chain assets or vaults, and building or operating liquidity mining programs. Strong understanding of protocol governance and how major DeFi protocols make integration and strategic decisions. Experience taking an asset, product, or solution through governance or protocol decision-making processes to achieve integration. Deep understanding of the lending and borrowing product landscape. Entrepreneurial mindset and genuine interest in building and scaling on-chain financial applications. Independent, self-directed approach with a strong drive to identify opportunities and deliver results. Strong relationship-building, communication, strategic thinking, and commercial judgment. Technical experience or a technical background is a plus. Traditional finance (TradFi) experience is a plus. Experience with CRM platforms such as HubSpot is a plus. Willingness to work as a full-time employee; the role does not support contractor or B2B arrangements. Benefits Full-time employment. Fully remote work arrangement. Opportunity to work closely with executive and product leadership. Senior-level ownership of commercial strategy, partnerships, and DeFi integrations. Exposure to leading participants across the crypto-native and broader DeFi ecosystem. Opportunity to influence product development through direct customer and market feedback. High-autonomy environment with significant entrepreneurial responsibility. Opportunity to contribute to the development and adoption of on-chain financial applications. Collaboration with experienced builders working across financial infrastructure, technology, crypto, banking, insurance, and financial services. Strategic exposure to emerging DeFi markets, liquidity mechanisms, governance, and on-chain capital markets.

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