Verified current Grant

INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed)

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Fundi...

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National Institutes of Health Source published May 12, 2026 Verified 10 hours ago
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DeadlineThu Jun 15 12:00 AM 2028
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Overview

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) is to solicit Transformative Research Award applications to support individual scientists or groups of scientists proposing groundbreaking, exceptionally innovative, original, and/or unconventional research that has the potentia...

Complete grant details

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) is to solicit Transformative Research Award applications to support individual scientists or groups of scientists proposing groundbreaking, exceptionally innovative, original, and/or unconventional research that has the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies related to Down syndrome. Applications are welcome in all topics relevant to Down syndrome-related research or its co-occurring conditions. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in research related to Down syndrome.

Eligible applicants Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); County governments; Private institutions of higher education; Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities; Special district governments; Native American tribal organizations (other than Federally recognized tribal governments); Independent school districts; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; State governments; City or township governments; For profit organizations other than small businesses

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Eligibility requirements

Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); County governments; Private institutions of higher education; Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities; Special district governments; Native American tribal organizations (other than Federally recognized tribal governments); Independent school districts; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; State governments; City or township governments; For profit organizations other than small businesses

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

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