Overview
The University of Zurich, Switzerland's largest university, offers a range of attractive positions in various subject areas and professional fields. With around 10,000 employees and currently 12 professional apprenticeship streams the University offers an inspiring working environment on cutting-edge research and top-class education. Put your talent and skills to work with us. Find out more about UZH as an employer! Your responsibilities Specific project goals: Generate CAR immune cell communities, comprising mixtures of engineered T cells, NK cells, monocytes, and additional cell types, using sophisticated in vitro and in vivo engineering platforms. Identify co-factors that boost CAR immune cell function using cutting-edge screening platforms. Investigate anti-tumor activity and immune-cancer-cell environmental crosstalk in vitro and in vivo using sophisticated disease models (organoids
Complete research opportunity details
Full Job Description
The University of Zurich, Switzerland's largest university, offers a range of attractive positions in various subject areas and professional fields. With around 10,000 employees and currently 12 professional apprenticeship streams the University offers an inspiring working environment on cutting-edge research and top-class education. Put your talent and skills to work with us. Find out more about UZH as an employer!
Your responsibilities
Specific project goals:
- Generate CAR immune cell communities, comprising mixtures of engineered T cells, NK cells, monocytes, and additional cell types, using sophisticated in vitro and in vivo engineering platforms.
- Identify co-factors that boost CAR immune cell function using cutting-edge screening platforms.
- Investigate anti-tumor activity and immune-cancer-cell environmental crosstalk in vitro and in vivo using sophisticated disease models (organoids, slice cultures, patient-derived samples, mouse models) and modern technologies including flow cytometry, multiplexed imaging, spatial transcriptomics/proteomics and single-cell profiling.
- Analyze patient samples from an accompanying clinical trial evaluating CAR immune cell communities.
Your profile
- Intellectual curiosity, creativity and a proactive approach to problem-solving
- Motivation to contribute to a project with direct patient impact
- PhD in immunology, computational immunology, cell/molecular/cancer biology, bioengineering, biomedical sciences, or a related field
- Experience with immune cell engineering, cellular immunotherapy, and/or advanced in vitro/in vivo disease models is highly desirable
- Familiarity with single-cell and/or spatial technologies is a plus
- Strong publication record demonstrating scientific productivity
- Excellent communication skills and the ability to thrive in an interdisciplinary team
Tobias Weiss Prof. Dr. med. Dr. sc. nat. tobias.weiss@usz.ch
Key responsibilities
Specific project goals:
- Generate CAR immune cell communities, comprising mixtures of engineered T cells, NK cells, monocytes, and additional cell types, using sophisticated in vitro and in vivo engineering platforms.
- Identify co-factors that boost CAR immune cell function using cutting-edge screening platforms.
- Investigate anti-tumor activity and immune-cancer-cell environmental crosstalk in vitro and in vivo using sophisticated disease models (organoids, slice cultures, patient-derived samples, mouse models) and modern technologies including flow cytometry, multiplexed imaging, spatial transcriptomics/proteomics and single-cell profiling.
- Analyze patient samples from an accompanying clinical trial evaluating CAR immune cell communities.
Qualifications And Requirements
- Intellectual curiosity, creativity and a proactive approach to problem-solvingMotivation to contribute to a project with direct patient impactPhD in immunology, computational immunology, cell/molecular/cancer biology, bioengineering, biomedical sciences, or a related fieldExperience with immune cell engineering, cellular immunotherapy, and/or advanced in vitro/in vivo disease models is highly desirableFamiliarity with single-cell and/or spatial technologies is a plusStrong publication record demonstrating scientific productivityExcellent communication skills and the ability to thrive in an interdisciplinary team
Eligibility requirements
- Intellectual curiosity, creativity and a proactive approach to problem-solvingMotivation to contribute to a project with direct patient impactPhD in immunology, computational immunology, cell/molecular/cancer biology, bioengineering, biomedical sciences, or a related fieldExperience with immune cell engineering, cellular immunotherapy, and/or advanced in vitro/in vivo disease models is highly desirableFamiliarity with single-cell and/or spatial technologies is a plusStrong publication record demonstrating scientific productivityExcellent communication skills and the ability to thrive in an interdisciplinary team
Tips for this postdoctoral opportunity
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- Match your research background to the project, laboratory, supervisor and required methods rather than applying only from the title.
- Prepare a focused academic CV, transcripts, publications and research statement or proposal when requested by the official call.
- Confirm funding duration, stipend/salary, tuition coverage, start date and eligibility for international applicants.
- Contact a supervisor before applying only when the official instructions recommend or require it.
Verification notes
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